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Clinically Approved Nanoparticle Imaging Agents.


ABSTRACT: Nanoparticles are a new class of imaging agent used for both anatomic and molecular imaging. Nanoparticle-based imaging exploits the signal intensity, stability, and biodistribution behavior of submicron-diameter molecular imaging agents. This review focuses on nanoparticles used in human medical imaging, with an emphasis on radionuclide imaging and MRI. Newer nanoparticle platforms are also discussed in relation to theranostic and multimodal uses.

SUBMITTER: Thakor AS 

PROVIDER: S-EPMC5126695 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature

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Clinically Approved Nanoparticle Imaging Agents.

Thakor Avnesh S AS   Jokerst Jesse V JV   Ghanouni Pejman P   Campbell Jos L JL   Mittra Erik E   Gambhir Sanjiv S SS  

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20161013 12


Nanoparticles are a new class of imaging agent used for both anatomic and molecular imaging. Nanoparticle-based imaging exploits the signal intensity, stability, and biodistribution behavior of submicron-diameter molecular imaging agents. This review focuses on nanoparticles used in human medical imaging, with an emphasis on radionuclide imaging and MRI. Newer nanoparticle platforms are also discussed in relation to theranostic and multimodal uses. ...[more]

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