Associations of blood lead levels with reproductive hormone levels in men and postmenopausal women: Results from the SPECT-China Study.

ABSTRACT: We examined whether blood lead levels (BLLs) were associated with reproductive hormone levels in a cross-sectional study using data from the SPECT-China study. We selected 2286 men and 1571 postmenopausal women without hormone replacement therapy. BLLs, blood cadmium, total testosterone (TT), oestradiol (E2), luteinizing hormone (LH), follicle stimulating hormone (FSH) and sex hormone binding globulin(SHBG) levels were measured. The results showed that median values (interquartile range) of BLLs were 44.00??g/L (29.00-62.30) for men and 41.00??g/L (27.00-59.81) for postmenopausal women. In linear regression, after adjusting for age, current smoking status, body mass index, systolic blood pressure, diabetes and blood cadmium level, TT (P for trend?=?0.001) and SHBG (P for trend?

SUBMITTER: Chen C 

PROVIDER: S-EPMC5127181 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature