Ontology highlight
ABSTRACT:
SUBMITTER: Davidson R
PROVIDER: S-EPMC5127554 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Davidson Reshma R Pontasch Josef A JA Wu Jian-Qiu JQ
PloS one 20161129 11
Glucan synthases synthesize glucans, complex polysaccharides that are the major components in fungal cell walls and division septa. Studying regulation of glucan synthases is important as they are essential for fungal cell survival and thus popular targets for anti-fungal drugs. Linear 1,3-β-glucan is the main component of primary septum and is synthesized by the conserved β-glucan synthase Bgs1 in fission yeast cytokinesis. It is known that Rho1 GTPase regulates Bgs1 catalytic activity and the ...[more]