Ontology highlight
ABSTRACT:
SUBMITTER: Kiser PD
PROVIDER: S-EPMC5132409 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Kiser Philip D PD Palczewski Krzysztof K
Annual review of vision science 20160718
Recent progress in molecular understanding of the retinoid cycle in mammalian retina stems from painstaking biochemical reconstitution studies supported by natural or engineered animal models with known genetic lesions and studies of humans with specific genetic blinding diseases. Structural and membrane biology have been used to detect critical retinal enzymes and proteins and their substrates and ligands, placing them in a cellular context. These studies have been supplemented by analytical ch ...[more]