Ontology highlight
ABSTRACT:
SUBMITTER: Mace EM
PROVIDER: S-EPMC5133264 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Mace Emily M EM Orange Jordan S JS
Frontiers in immunology 20161202
Human NK cells play critical roles in human host defense, particularly the control of viral infection and malignancy, and patients with congenital immunodeficiency affecting NK cell function or number can suffer from severe illness. The importance of NK cell function is particularly underscored in patients with primary immunodeficiency in which NK cells are the primary or sole affected population (NK cell deficiency, NKD). While NKD may lead to the absence of NK cells, we are also gaining an inc ...[more]