Ontology highlight
ABSTRACT:
SUBMITTER: Koppes RA
PROVIDER: S-EPMC5134911 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Biomaterials 20151202
Synthetic neural scaffolds hold promise to eventually replace nerve autografts for tissue repair following peripheral nerve injury. Despite substantial evidence for the influence of scaffold geometry and dimensions on the rate of axonal growth, systematic evaluation of these parameters remains a challenge due to limitations in materials processing. We have employed fiber drawing to engineer a wide spectrum of polymer-based neural scaffolds with varied geometries and core sizes. Using isolated wh ...[more]