Ontology highlight
ABSTRACT:
SUBMITTER: Cala AR
PROVIDER: S-EPMC5137465 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Acta crystallographica. Section F, Structural biology communications 20161125 Pt 12
In bacteria, the second committed step in the diaminopimelate/lysine anabolic pathways is catalyzed by the enzyme dihydrodipicolinate reductase (DapB). DapB catalyzes the reduction of dihydrodipicolinate to yield tetrahydrodipicolinate. Here, the cloning, expression, purification, crystallization and X-ray diffraction analysis of DapB from the human-pathogenic bacterium Bartonella henselae, the causative bacterium of cat-scratch disease, are reported. Protein crystals were grown in conditions co ...[more]