Ontology highlight
ABSTRACT:
SUBMITTER: Potter RF
PROVIDER: S-EPMC5140036 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20160919
Carbapenems, our one-time silver bullet for multidrug resistant bacterial infections, are now threatened by widespread dissemination of carbapenem-resistant Enterobacteriaceae (CRE). Successful expansion of Enterobacteriaceae clonal groups and frequent horizontal gene transfer of carbapenemase expressing plasmids are causing increasing carbapenem resistance. Recent advances in genetic and phenotypic detection facilitate global surveillance of CRE diversity and prevalence. In particular, whole ge ...[more]