Ontology highlight
ABSTRACT:
SUBMITTER: Aurora M
PROVIDER: S-EPMC5140713 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Aurora Megan M Spence Jason R JR
Developmental biology 20160607 2
In vitro human pluripotent stem cell (hPSC) derived tissues are excellent models to study certain aspects of normal human development. Current research in the field of hPSC derived tissues reveals these models to be inherently fetal-like on both a morphological and gene expression level. In this review we briefly discuss current methods for differentiating lung and intestinal tissue from hPSCs into individual 3-dimensional units called organoids. We discuss how these methods mirror what is known ...[more]