Ontology highlight
ABSTRACT:
SUBMITTER: Kwon H
PROVIDER: S-EPMC5141285 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Nature communications 20161129
Catalytic heme enzymes carry out a wide range of oxidations in biology. They have in common a mechanism that requires formation of highly oxidized ferryl intermediates. It is these ferryl intermediates that provide the catalytic engine to drive the biological activity. Unravelling the nature of the ferryl species is of fundamental and widespread importance. The essential question is whether the ferryl is best described as a Fe(IV)=O or a Fe(IV)-OH species, but previous spectroscopic and X-ray cr ...[more]