Ontology highlight
ABSTRACT:
SUBMITTER: Botte M
PROVIDER: S-EPMC5141469 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Botte Mathieu M Zaccai Nathan R NR Nijeholt Jelger Lycklama À JL Martin Remy R Knoops Kèvin K Papai Gabor G Zou Juan J Deniaud Aurélien A Karuppasamy Manikandan M Jiang Qiyang Q Roy Abhishek Singha AS Schulten Klaus K Schultz Patrick P Rappsilber Juri J Zaccai Giuseppe G Berger Imre I Collinson Ian I Schaffitzel Christiane C
Scientific reports 20161207
The conserved SecYEG protein-conducting channel and the accessory proteins SecDF-YajC and YidC constitute the bacterial holo-translocon (HTL), capable of protein-secretion and membrane-protein insertion. By employing an integrative approach combining small-angle neutron scattering (SANS), low-resolution electron microscopy and biophysical analyses we determined the arrangement of the proteins and lipids within the super-complex. The results guided the placement of X-ray structures of individual ...[more]