Ontology highlight
ABSTRACT:
SUBMITTER: Ersche KD
PROVIDER: S-EPMC5144994 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Ersche Karen D KD Gillan Claire M CM Jones P Simon PS Williams Guy B GB Ward Laetitia H E LH Luijten Maartje M de Wit Sanne S Sahakian Barbara J BJ Bullmore Edward T ET Robbins Trevor W TW
Science (New York, N.Y.) 20160601 6292
Cocaine addiction is a major public health problem that is particularly difficult to treat. Without medically proven pharmacological treatments, interventions to change the maladaptive behavior of addicted individuals mainly rely on psychosocial approaches. Here we report on impairments in cocaine-addicted patients to act purposefully toward a given goal and on the influence of extended training on their behavior. When patients were rewarded for their behavior, prolonged training improved their ...[more]