Ontology highlight
ABSTRACT:
SUBMITTER: Contoli M
PROVIDER: S-EPMC5147412 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Contoli Marco M Solidoro Paolo P Di Marco Fabiano F Scichilone Nicola N Corsico Angelo A Braido Fulvio F Santus Pierachille P
International journal of chronic obstructive pulmonary disease 20161205
The pathophysiology of chronic obstructive pulmonary disease (COPD) includes persistent airflow limitation, altered gas exchange, and enhanced chronic inflammatory response. According to disease severity in individual patients, exacerbations and comorbidities frequently occur. The overall nocturnal and daily symptoms have a strong impact on patient quality of life and clinical outcomes. Bronchodilators, by targeting two important aspects of COPD pathophysiology, ie, bronchoconstriction and lung ...[more]