Neural Architecture of Hunger-Dependent Multisensory Decision Making in C. elegans.
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ABSTRACT:
SUBMITTER: Ghosh DD
PROVIDER: S-EPMC5147516 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Publications
Neural Architecture of Hunger-Dependent Multisensory Decision Making in C. elegans.
Ghosh D Dipon DD Sanders Tom T Hong Soonwook S McCurdy Li Yan LY Chase Daniel L DL Cohen Netta N Koelle Michael R MR Nitabach Michael N MN
Neuron 20161117 5
Little is known about how animals integrate multiple sensory inputs in natural environments to balance avoidance of danger with approach to things of value. Furthermore, the mechanistic link between internal physiological state and threat-reward decision making remains poorly understood. Here we confronted C. elegans worms with the decision whether to cross a hyperosmotic barrier presenting the threat of desiccation to reach a source of food odor. We identified a specific interneuron that contro ...[more]
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