Ontology highlight
ABSTRACT:
SUBMITTER: Thongnak C
PROVIDER: S-EPMC5149683 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Thongnak Chuphong C Limprasert Pornprot P Tangviriyapaiboon Duangkamol D Silvilairat Suchaya S Puangpetch Apichaya A Pasomsub Ekawat E Sukasem Chonlaphat C Chantratita Wasun W
Disease markers 20161128
<i>Background</i>. Congenital heart block is characterized by blockage of electrical impulses from the atrioventricular node (AV node) to the ventricles. This blockage can be caused by ion channel impairment that is the result of genetic variation. This study aimed to investigate the possible causative variants in a Thai family with complete heart block by using whole exome sequencing. <i>Methods</i>. Genomic DNA was collected from a family consisting of five family members in three generations ...[more]