Ontology highlight
ABSTRACT:
SUBMITTER: Pevzner PA
PROVIDER: S-EPMC515325 | biostudies-literature | 2004 Sep
REPOSITORIES: biostudies-literature
Pevzner Pavel A PA Tang Haixu H Tesler Glenn G
Genome research 20040901 9
Repetitive sequences make up a significant fraction of almost any genome, and an important and still open question in bioinformatics is how to represent all repeats in DNA sequences. We propose a new approach to repeat classification that represents all repeats in a genome as a mosaic of sub-repeats. Our key algorithmic idea also leads to new approaches to multiple alignment and fragment assembly. In particular, we show that our FragmentGluer assembler improves on Phrap and ARACHNE in assembly o ...[more]