Predicting learning plateau of working memory from whole-brain intrinsic network connectivity patterns.

ABSTRACT: Individual learning performance of cognitive function is related to functional connections within 'task-activated' regions where activities increase during the corresponding cognitive tasks. On the other hand, since any brain region is connected with other regions and brain-wide networks, learning is characterized by modulations in connectivity between networks with different functions. Therefore, we hypothesized that learning performance is determined by functional connections among intrinsic networks that include both task-activated and less-activated networks. Subjects underwent resting-state functional MRI and a short period of training (80-90 min) in a working memory task on separate days. We calculated functional connectivity patterns of whole-brain intrinsic networks and examined wh

SUBMITTER: Yamashita M 

PROVIDER: S-EPMC5154600 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature