Ontology highlight
ABSTRACT:
SUBMITTER: Hellstrom A
PROVIDER: S-EPMC5154870 | biostudies-literature | 2016 Oct - Dec
REPOSITORIES: biostudies-literature
Hellström Ann A Ley David D Hansen-Pupp Ingrid I Hallberg Boubou B Ramenghi Luca A LA Löfqvist Chatarina C Smith Lois E H LE Hård Anna-Lena AL
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20160928
Retinopathy of prematurity is a potentially blinding disease, which is associated with low neonatal IGF-I serum concentrations and poor growth. In severe cases impaired retinal vessel growth is followed by pathologic neovascularization, which may lead to retinal detachment. IGF-I may promote growth even in catabolic states. Treating preterm infants with recombinant human (rh) IGF-I to concentrations normally found during gestation has been suggested to have a preventative effect on ROP. A recent ...[more]