Ontology highlight
ABSTRACT:
SUBMITTER: Verma SK
PROVIDER: S-EPMC5155008 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Verma Shailendra Kumar SK Tuteja Urmil U
Frontiers in immunology 20161214
Plague is one of the world's most lethal human diseases caused by <i>Yersinia pestis</i>, a Gram-negative bacterium. Despite overwhelming studies for many years worldwide, there is no safe and effective vaccine against this fatal disease. Inhalation of <i>Y. pestis</i> bacilli causes pneumonic plague, a fast growing and deadly dangerous disease. F1/LcrV-based vaccines failed to provide adequate protection in African green monkey model in spite of providing protection in mice and cynomolgus macaq ...[more]