Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994.
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ABSTRACT:
SUBMITTER: Jelenkovic A
PROVIDER: S-EPMC5156525 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Publications
Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994.
Jelenkovic Aline A Hur Yoon-Mi YM Sund Reijo R Yokoyama Yoshie Y Siribaddana Sisira H SH Hotopf Matthew M Sumathipala Athula A Rijsdijk Fruhling F Tan Qihua Q Zhang Dongfeng D Pang Zengchang Z Aaltonen Sari S Heikkilä Kauko K Öncel Sevgi Y SY Aliev Fazil F Rebato Esther E Tarnoki Adam D AD Tarnoki David L DL Christensen Kaare K Skytthe Axel A Kyvik Kirsten O KO Silberg Judy L JL Eaves Lindon J LJ Maes Hermine H HH Cutler Tessa L TL Hopper John L JL Ordoñana Juan R JR Sánchez-Romera Juan F JF Colodro-Conde Lucia L Cozen Wendy W Hwang Amie E AE Mack Thomas M TM Sung Joohon J Song Yun-Mi YM Yang Sarah S Lee Kayoung K Franz Carol E CE Kremen William S WS Lyons Michael J MJ Busjahn Andreas A Nelson Tracy L TL Whitfield Keith E KE Kandler Christian C Jang Kerry L KL Gatz Margaret M Butler David A DA Stazi Maria A MA Fagnani Corrado C D'Ippolito Cristina C Duncan Glen E GE Buchwald Dedra D Derom Catherine A CA Vlietinck Robert F RF Loos Ruth Jf RJ Martin Nicholas G NG Medland Sarah E SE Montgomery Grant W GW Jeong Hoe-Uk HU Swan Gary E GE Krasnow Ruth R Magnusson Patrik Ke PK Pedersen Nancy L NL Dahl-Aslan Anna K AK McAdams Tom A TA Eley Thalia C TC Gregory Alice M AM Tynelius Per P Baker Laura A LA Tuvblad Catherine C Bayasgalan Gombojav G Narandalai Danshiitsoodol D Lichtenstein Paul P Spector Timothy D TD Mangino Massimo M Lachance Genevieve G Bartels Meike M van Beijsterveldt Toos Cem TC Willemsen Gonneke G Burt S Alexandra SA Klump Kelly L KL Harris Jennifer R JR Brandt Ingunn I Nilsen Thomas Sevenius TS Krueger Robert F RF McGue Matt M Pahlen Shandell S Corley Robin P RP Hjelmborg Jacob V B JV Goldberg Jack H JH Iwatani Yoshinori Y Watanabe Mikio M Honda Chika C Inui Fujio F Rasmussen Finn F Huibregtse Brooke M BM Boomsma Dorret I DI Sørensen Thorkild I A TI Kaprio Jaakko J Silventoinen Karri K
eLife 20161214
Human height variation is determined by genetic and environmental factors, but it remains unclear whether their influences differ across birth-year cohorts. We conducted an individual-based pooled analysis of 40 twin cohorts including 143,390 complete twin pairs born 1886-1994. Although genetic variance showed a generally increasing trend across the birth-year cohorts, heritability estimates (0.69-0.84 in men and 0.53-0.78 in women) did not present any clear pattern of secular changes. Comparing ...[more]
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