Viral factors in influenza pandemic risk assessment.
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ABSTRACT:
SUBMITTER: Lipsitch M
PROVIDER: S-EPMC5156527 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Publications
Viral factors in influenza pandemic risk assessment.
Lipsitch Marc M Barclay Wendy W Raman Rahul R Russell Charles J CJ Belser Jessica A JA Cobey Sarah S Kasson Peter M PM Lloyd-Smith James O JO Maurer-Stroh Sebastian S Riley Steven S Beauchemin Catherine Aa CA Bedford Trevor T Friedrich Thomas C TC Handel Andreas A Herfst Sander S Murcia Pablo R PR Roche Benjamin B Wilke Claus O CO Russell Colin A CA
eLife 20161111
The threat of an influenza A virus pandemic stems from continual virus spillovers from reservoir species, a tiny fraction of which spark sustained transmission in humans. To date, no pandemic emergence of a new influenza strain has been preceded by detection of a closely related precursor in an animal or human. Nonetheless, influenza surveillance efforts are expanding, prompting a need for tools to assess the pandemic risk posed by a detected virus. The goal would be to use genetic sequence and/ ...[more]
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