Quantifying dorsal closure in three dimensions.
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ABSTRACT:
SUBMITTER: Lu H
PROVIDER: S-EPMC5156535 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Publications
Quantifying dorsal closure in three dimensions.
Lu Heng H Sokolow Adam A Kiehart Daniel P DP Edwards Glenn S GS
Molecular biology of the cell 20161026 25
Dorsal closure is an essential stage of Drosophila embryogenesis and is a powerful model system for morphogenesis, wound healing, and tissue biomechanics. During closure, two flanks of lateral epidermis close an eye-shaped dorsal opening that is filled with amnioserosa. The two flanks of lateral epidermis are zipped together at each canthus ("corner" of the eye). Actomyosin-rich purse strings are localized at each of the two leading edges of lateral epidermis ("lids" of the eye). Here we report ...[more]
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