Ontology highlight
ABSTRACT:
SUBMITTER: Zaman M
PROVIDER: S-EPMC5157026 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Zaman Mehfuz M Ozberk Victoria V Langshaw Emma L EL McPhun Virginia V Powell Jessica L JL Phillips Zachary N ZN Ho Mei Fong MF Calcutt Ainslie A Batzloff Michael R MR Toth Istvan I Hill Geoffrey R GR Pandey Manisha M Good Michael F MF
Scientific reports 20161215
The upper respiratory tract (URT) is the major entry site for human pathogens and strategies to activate this network could lead to new vaccines capable of preventing infection with many pathogens. Group A streptococcus (GAS) infections, causing rheumatic fever, rheumatic heart disease, and invasive disease, are responsible for substantial morbidity and mortality. We describe an innovative vaccine strategy to induce mucosal antibodies of significant magnitude against peptide antigens of GAS usin ...[more]