Changes in connectivity profiles define functionally distinct regions in human medial frontal cortex.
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ABSTRACT:
SUBMITTER: Johansen-Berg H
PROVIDER: S-EPMC516567 | biostudies-literature | 2004 Sep
REPOSITORIES: biostudies-literature
Publications
Changes in connectivity profiles define functionally distinct regions in human medial frontal cortex.
Johansen-Berg H H Behrens T E J TE Robson M D MD Drobnjak I I Rushworth M F S MF Brady J M JM Smith S M SM Higham D J DJ Matthews P M PM
Proceedings of the National Academy of Sciences of the United States of America 20040830 36
A fundamental issue in neuroscience is the relation between structure and function. However, gross landmarks do not correspond well to microstructural borders and cytoarchitecture cannot be visualized in a living brain used for functional studies. Here, we used diffusion-weighted and functional MRI to test structure-function relations directly. Distinct neocortical regions were defined as volumes having similar connectivity profiles and borders identified where connectivity changed. Without usin ...[more]
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