Ontology highlight
ABSTRACT:
SUBMITTER: Walter RF
PROVIDER: S-EPMC5166524 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Walter Robert Fred Henry RF Vollbrecht Claudia C Christoph Daniel D Werner Robert R Schmeller Jan J Flom Elena E Trakada Georgia G Rapti Aggeliki A Adamidis Vasilis V Hohenforst-Schmidt Wolfgang W Kollmeier Jens J Mairinger Thomas T Wohlschlaeger Jeremias J Zarogoulidis Paul P Porpodis Konstantinos K Schmidt Kurt Werner KW Mairinger Fabian Dominik FD
Journal of Cancer 20161025 15
<b>Background</b>: Lung cancer is the leading cause of cancer-related deaths worldwide. 25% show neuroendocrine differentiation (typical/atypical carcinoids, large-/small-cell neuroendocrine carcinomas). Carcinoids present with long survival rates, but metastatic carcinoids correlate with decreased survival and are commonly insensitive to standard chemotherapy or radiation. Therefore, novel therapeutic strategies are urgently needed. <b>Material and methods</b>: 70 representative tumor specimens ...[more]