Ontology highlight
ABSTRACT:
SUBMITTER: Peters ME
PROVIDER: S-EPMC5166612 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Peters Matthew E ME Vaidya Vijay V Drye Lea T LT Devanand Davangere P DP Mintzer Jacobo E JE Pollock Bruce G BG Porsteinsson Anton P AP Rosenberg Paul B PB Schneider Lon S LS Shade David M DM Weintraub Daniel D Yesavage Jerome J Lyketsos Constantine G CG Avramopoulos Dimitri D
Journal of geriatric psychiatry and neurology 20150823 2
<h4>Objective</h4>To assess potential genetic influences on citalopram treatment efficacy for agitation in individuals with Alzheimer dementia (AD). Six functional genetic variants were studied in the following genes: serotonin receptor 2A (HTR2A-T102C), serotonin receptor 2C (HTR2C-Cys23Ser), serotonin transporter (5HTT-LPR), brain-derived neurotropic factor (BDNF-Val66Met), apolipoprotein E (ε2, ε3, ε4 variants), and cytochrome P450 (CYP2C19). Treatment response by genotype was measured by (1) ...[more]