Ontology highlight
ABSTRACT:
SUBMITTER: Lockhead D
PROVIDER: S-EPMC5170555 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Lockhead Dean D Schwarz Erich M EM O'Hagan Robert R Bellotti Sebastian S Krieg Michael M Barr Maureen M MM Dunn Alexander R AR Sternberg Paul W PW Goodman Miriam B MB
Molecular biology of the cell 20160921
Microtubules contribute to many cellular processes, including transport, signaling, and chromosome separation during cell division (Kapitein and Hoogenraad, 2015). They are comprised of αβ-tubulin heterodimers arranged into linear protofilaments and assembled into tubes. Eukaryotes express multiple tubulin isoforms (Gogonea et al., 1999), and there has been a longstanding debate as to whether the isoforms are redundant or perform specialized roles as part of a tubulin code (Fulton and Simpson, 1 ...[more]