Structure prediction of membrane proteins.
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ABSTRACT:
SUBMITTER: Zhou C
PROVIDER: S-EPMC5172438 | biostudies-literature | 2004 Feb
REPOSITORIES: biostudies-literature
Publications
Structure prediction of membrane proteins.
Zhou Chunlong C Zheng Yao Y Zhou Yan Y
Genomics, proteomics & bioinformatics 20040201 1
There is a large gap between the number of membrane protein (MP) sequences and that of their decoded 3D structures, especially high-resolution structures, due to difficulties in crystal preparation of MPs. However, detailed knowledge of the 3D structure is required for the fundamental understanding of the function of an MP and the interactions between the protein and its inhibitors or activators. In this paper, some computational approaches that have been used to predict MP structures are discus ...[more]
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