Ontology highlight
ABSTRACT:
SUBMITTER: Jones AM
PROVIDER: S-EPMC5173039 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Jones Angela M AM Ferguson Peter P Gardner Jacqui J Rooker Serena S Sutton Tim T Ahn Antonio A Chatterjee Aniruddha A Bickley Vivienne M VM Sarwar Makhdoom M Emanuel Patrick P Kenwright Diane D Shepherd Peter R PR Eccles Michael R MR
Oncotarget 20160701 27
Melanoma, the most aggressive skin cancer type, is responsible for 75% of skin cancer related deaths worldwide. Given that New Zealand (NZ) has the world's highest melanoma incidence, we sought to determine the frequency of mutations in NZ melanomas in recurrently mutated genes. NZ melanomas were from localities distributed between North (35°S-42°S) and South Islands (41°S-47°S). A total of 529 melanomas were analyzed for BRAF exon 15 mutations by Sanger sequencing, and also by Sequenom MelaCart ...[more]