Ontology highlight
ABSTRACT:
SUBMITTER: Werner RA
PROVIDER: S-EPMC5173054 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Werner Rudolf A RA Beykan Seval S Higuchi Takahiro T Lückerath Katharina K Weich Alexander A Scheurlen Michael M Bluemel Christina C Herrmann Ken K Buck Andreas K AK Lassmann Michael M Lapa Constantin C Hänscheid Heribert H
Oncotarget 20160701 27
Peptide Receptor Radionuclide Therapy (PRRT) for the treatment of neuroendocrine tumors may lead to kidney deterioration. This study aimed to evaluate the suitability of 99mTc-mercaptoacetyltriglycine (99mTc--MAG3) clearance for the early detection of PRRT-induced changes on tubular extraction (TE). TE rate (TER) was measured prior to 128 PRRT cycles (7.6±0.4 GBq 177Lu-octreotate/octreotide each) in 32 patients. TER reduction during PRRT was corrected for age-related decrease and analyzed for th ...[more]