Ontology highlight
ABSTRACT:
SUBMITTER: de Cristofaro T
PROVIDER: S-EPMC5173106 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
de Cristofaro Tiziana T Di Palma Tina T Soriano Amata Amy AA Monticelli Antonella A Affinito Ornella O Cocozza Sergio S Zannini Mariastella M
Oncotarget 20160701 27
Understanding the biology and molecular pathogenesis of ovarian epithelial cancer (EOC) is key to developing improved diagnostic and prognostic indicators and effective therapies. Although research has traditionally focused on the hypothesis that high-grade serous carcinoma (HGSC) arises from the ovarian surface epithelium (OSE), recent studies suggest that additional sites of origin exist and a substantial proportion of cases may arise from precursor lesions located in the Fallopian tubal epith ...[more]