Dataset Information

Cancer incidence attributable to tobacco in Alberta, Canada, in 2012.

ABSTRACT:

Background

Strong and consistent epidemiologic evidence shows that tobacco smoking causes cancers at various sites. The purpose of this study was to quantify the proportion and total number of site-specific cancers in Alberta attributable to tobacco exposure.

Methods

The proportion of incident cancer cases attributable to active and passive tobacco exposure in Alberta was estimated with population attributable risks. Data from the Canadian Community Health Survey (CCHS) for 2000-2007 were used to estimate prevalence of active (current or former smoker) and passive (second-hand smoke) tobacco exposure in Alberta.

Results

According to the 2000/01 CCHS, 29.1% and 38.6% of Albertans were estimated to be current and former smokers, respectively. According to the 2003 CCHS, 23.7% of Albertans who had never smoked reported regular second-hand exposure to tobacco. Population attributable risk estimates for tobacco-related cancer sites ranged from about 4% for ovarian cancer to 74% for laryngeal cancer. About 5% of incident lung cancers in men and women who never smoked could be attributed to passive tobacco exposure. Overall, 37.0% of tobacco-related cancers in Alberta (or 15.7% of all cancers) were estimated to be attributable to active tobacco smoking in 2012.

Interpretation

A notable proportion of cancers associated with tobacco use were estimated to be attributable to active smoking in Alberta. Strategies to reduce the prevalence of active tobacco smoking in Alberta could have a considerable impact on future cancer incidence.

SUBMITTER: Poirier AE

PROVIDER: S-EPMC5173469 | biostudies-literature | 2016 Oct-Dec

REPOSITORIES: biostudies-literature

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Publications

Cancer incidence attributable to tobacco in Alberta, Canada, in 2012.

Poirier Abbey E AE Grundy Anne A Khandwala Farah F Tamminen Sierra S Friedenreich Christine M CM Brenner Darren R DR

CMAJ open 20161013 4

<h4>Background</h4>Strong and consistent epidemiologic evidence shows that tobacco smoking causes cancers at various sites. The purpose of this study was to quantify the proportion and total number of site-specific cancers in Alberta attributable to tobacco exposure.<h4>Methods</h4>The proportion of incident cancer cases attributable to active and passive tobacco exposure in Alberta was estimated with population attributable risks. Data from the Canadian Community Health Survey (CCHS) for 2000-2 ...[more]

PMID: 28018870

Similar Datasets

Project description:BackgroundEstimates of the proportion of cancer cases that can be attributed to modifiable risk factors are not available for Canada and, more specifically, Alberta. The purpose of this study was to estimate the total proportion of cancer cases in Alberta in 2012 that could be attributed to a set of 24 modifiable lifestyle and environmental risk factors.MethodsWe estimated summary population attributable risk estimates for 24 risk factors (smoking [both passive and active], overweight and obesity, inadequate physical activity, diet [inadequate fruit and vegetable consumption, inadequate fibre intake, excess red and processed meat consumption, salt consumption, inadequate calcium and vitamin D intake], alcohol, hormones [oral contraceptives and hormone therapy], infections [Epstein-Barr virus, hepatitis B and C viruses, human papillomavirus, Helicobacter pylori], air pollution, natural and artificial ultraviolet radiation, radon and water disinfection by-products) by combining population attributable risk estimates for each of the 24 factors that had been previously estimated. To account for the possibility that individual cancer cases were the result of a combination of multiple risk factors, we subtracted the population attributable risk for the first factor from 100% and then applied the population attributable risk for the second factor to the remaining proportion that was not attributable to the first factor. We repeated this process in sequential order for all relevant exposures.ResultsOverall, an estimated 40.8% of cancer cases in Alberta in 2012 were attributable to modifiable lifestyle and environmental risk factors. The largest proportion of cancers were estimated to be attributable to tobacco smoking, physical inactivity and excess body weight. The summary population attributable risk estimate was slightly higher among women (42.4%) than among men (38.7%).InterpretationAbout 41% of cancer cases in Alberta may be attributable to known modifiable lifestyle and environmental risk factors. Reducing the prevalence of these factors in the Alberta population has the potential to substantially reduce the provincial cancer burden.

Dataset Information

Cancer incidence attributable to tobacco in Alberta, Canada, in 2012.

Background

Methods

Results

Interpretation

Publications

Cancer incidence attributable to tobacco in Alberta, Canada, in 2012.

Similar Datasets

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