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Use of deoxyribose by intestinal and extraintestinal pathogenic Escherichia coli strains: a metabolic adaptation involved in competitiveness.


ABSTRACT: We showed that the deoK operon, which confers the ability to use deoxyribose as a carbon source, is more common among pathogenic than commensal Escherichia coli strains. The expression of the deoK operon increases the competitiveness of clinical isolates, suggesting that this biochemical characteristic plays a role in host infectivity.

SUBMITTER: Bernier-Febreau C 

PROVIDER: S-EPMC517565 | biostudies-literature | 2004 Oct

REPOSITORIES: biostudies-literature

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Use of deoxyribose by intestinal and extraintestinal pathogenic Escherichia coli strains: a metabolic adaptation involved in competitiveness.

Bernier-Fébreau Christine C   du Merle Laurence L   Turlin Evelyne E   Labas Valérie V   Ordonez Juana J   Gilles Anne-Marie AM   Le Bouguénec Chantal C  

Infection and immunity 20041001 10


We showed that the deoK operon, which confers the ability to use deoxyribose as a carbon source, is more common among pathogenic than commensal Escherichia coli strains. The expression of the deoK operon increases the competitiveness of clinical isolates, suggesting that this biochemical characteristic plays a role in host infectivity. ...[more]

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