Dataset Information

Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children.

ABSTRACT:

Objective

To investigate the minimum optimal acquisition number of hepatic shear wave velocities (SWVs) on ultrasound elastography in children.

Materials and methods

We prospectively performed hepatic supersonic shear wave elastography in children of four groups (group A-C, healthy children, group A with 0-5 years old; group B with 6-10 years old; group C with 11-18 years old; and group D, children with previous Kasai operation) with free breathing (FB) and breath holding (BH) status, if possible. SWVs were measured fifteen times for each child at a 4 cm depth for the right lobe using a 1-6 MHz convex transducer. Mean SWVs from three, five, and seven acquisitions were compared to the mean SWV from fifteen measurements, using an intraclass correlation coefficient (ICC) analyzed with the 1,000 times bootstrap method.

Results

Total eighty-eight children were included (25 children in group A, 30 children in group B, 21 children in group C, and 12 children in group D). The mean SWVs from fifteen measurements in FB status were 5.5 ± 1.3 kPa for groups A-C together and 8.0 ± 2.2 kPa for group D. For all groups together, mean SWVs from the three (ICC 0.944 and 0.937), five (ICC 0.958 and 0.938) and seven (ICC 0.969 and 0.941) acquisitions demonstrated almost perfect agreement with the reference of fifteen acquisitions in both FB and BH status, respectively. A subgroup analysis showed three measurements were in almost perfect agreement during FB for groups B-D and strong agreement (ICC 0.675) for group A.

Conclusion

Three acquisitions can be enough for hepatic SWVs in children more than 6 years old regardless of breathing status or hepatic pathology. More acquisitions are recommended for children under the age of 5 years during FB.

SUBMITTER: Shin HJ

PROVIDER: S-EPMC5176183 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Publications

Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children.

Shin Hyun Joo HJ Kim Myung-Joon MJ Kim Ha Yan HY Roh Yun Ho YH Lee Mi-Jung MJ

PloS one 20161221 12

<h4>Objective</h4>To investigate the minimum optimal acquisition number of hepatic shear wave velocities (SWVs) on ultrasound elastography in children.<h4>Materials and methods</h4>We prospectively performed hepatic supersonic shear wave elastography in children of four groups (group A-C, healthy children, group A with 0-5 years old; group B with 6-10 years old; group C with 11-18 years old; and group D, children with previous Kasai operation) with free breathing (FB) and breath holding (BH) sta ...[more]

PMID: 28002480

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Dataset Information

Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children.

Objective

Materials and methods

Results

Conclusion

Publications

Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children.

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