Ontology highlight
ABSTRACT:
SUBMITTER: Pfau ML
PROVIDER: S-EPMC5179560 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Pfau Madeline L ML Purushothaman Immanuel I Feng Jian J Golden Sam A SA Aleyasin Hossein H Lorsch Zachary S ZS Cates Hannah M HM Flanigan Meghan E ME Menard Caroline C Heshmati Mitra M Wang Zichen Z Ma'ayan Avi A Shen Li L Hodes Georgia E GE Russo Scott J SJ
Frontiers in molecular neuroscience 20161223
Adult women are twice as likely as men to suffer from affective and anxiety disorders, although the mechanisms underlying heightened female stress susceptibility are incompletely understood. Recent findings in mouse Nucleus Accumbens (NAc) suggest a role for DNA methylation-driven sex differences in genome-wide transcriptional profiles. However, the role of another epigenetic process-microRNA (miR) regulation-has yet to be explored. We exposed male and female mice to Subchronic Variable Stress ( ...[more]