Androgen Receptor: A Complex Therapeutic Target for Breast Cancer.
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ABSTRACT:
SUBMITTER: Narayanan R
PROVIDER: S-EPMC5187506 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Publications
Androgen Receptor: A Complex Therapeutic Target for Breast Cancer.
Narayanan Ramesh R Dalton James T JT
Cancers 20161202 12
Molecular and histopathological profiling have classified breast cancer into multiple sub-types empowering precision treatment. Although estrogen receptor (ER) and human epidermal growth factor receptor (HER2) are the mainstay therapeutic targets in breast cancer, the androgen receptor (AR) is evolving as a molecular target for cancers that have developed resistance to conventional treatments. The high expression of AR in breast cancer and recent discovery and development of new nonsteroidal dru ...[more]
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