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Highly Pathogenic Reassortant Avian Influenza A(H5N1) Virus Clade 2.3.2.1a in Poultry, Bhutan.

ABSTRACT: Highly pathogenic avian influenza A(H5N1), clade 2.3.2.1a, with an H9-like polymerase basic protein 1 gene, isolated in Bhutan in 2012, replicated faster in vitro than its H5N1 parental genotype and was transmitted more efficiently in a chicken model. These properties likely help limit/eradicate outbreaks, combined with strict control measures.

SUBMITTER: Marinova-Petkova A

PROVIDER: S-EPMC5189144 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature

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Highly Pathogenic Reassortant Avian Influenza A(H5N1) Virus Clade 2.3.2.1a in Poultry, Bhutan.

Marinova-Petkova Atanaska A Franks John J Tenzin Sangay S Dahal Narapati N Dukpa Kinzang K Dorjee Jambay J Feeroz Mohammed M MM Rehg Jerold E JE Barman Subrata S Krauss Scott S McKenzie Pamela P Webby Richard J RJ Webster Robert G RG

Emerging infectious diseases 20161215 12

Highly pathogenic avian influenza A(H5N1), clade 2.3.2.1a, with an H9-like polymerase basic protein 1 gene, isolated in Bhutan in 2012, replicated faster in vitro than its H5N1 parental genotype and was transmitted more efficiently in a chicken model. These properties likely help limit/eradicate outbreaks, combined with strict control measures. ...[more]

PMID: 27584733

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