Ontology highlight
ABSTRACT:
SUBMITTER: Kuchibhotla KV
PROVIDER: S-EPMC5191967 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Kuchibhotla Kishore V KV Gill Jonathan V JV Lindsay Grace W GW Papadoyannis Eleni S ES Field Rachel E RE Sten Tom A Hindmarsh TA Miller Kenneth D KD Froemke Robert C RC
Nature neuroscience 20161031 1
Physical features of sensory stimuli are fixed, but sensory perception is context dependent. The precise mechanisms that govern contextual modulation remain unknown. Here, we trained mice to switch between two contexts: passively listening to pure tones and performing a recognition task for the same stimuli. Two-photon imaging showed that many excitatory neurons in auditory cortex were suppressed during behavior, while some cells became more active. Whole-cell recordings showed that excitatory i ...[more]