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ABSTRACT:
SUBMITTER: Gonzalez-Rodriguez D
PROVIDER: S-EPMC5192693 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Gonzalez-Rodriguez David D Guillou Lionel L Cornat François F Lafaurie-Janvore Julie J Babataheri Avin A de Langre Emmanuel E Barakat Abdul I AI Husson Julien J
Biophysical journal 20161201 12
We investigate the mechanical conditions leading to the rupture of the plasma membrane of an endothelial cell subjected to a local, compressive force. Membrane rupture is induced by tilted microindentation, a technique used to perform mechanical measurements on adherent cells. In this technique, the applied force can be deduced from the measured horizontal displacement of a microindenter's tip, as imaged with an inverted microscope and without the need for optical sensors to measure the microind ...[more]