Diffusion tensor imaging measures of white matter compared to myelin basic protein immunofluorescence in tissue cleared intact brains.
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ABSTRACT:
SUBMITTER: Chang EH
PROVIDER: S-EPMC5198630 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Publications
Diffusion tensor imaging measures of white matter compared to myelin basic protein immunofluorescence in tissue cleared intact brains.
Chang Eric H EH Argyelan Miklos M Aggarwal Manisha M Chandon Toni-Shay S TS Karlsgodt Katherine H KH Mori Susumu S Malhotra Anil K AK
Data in brief 20161218
We provide datasets from combined <i>ex vivo</i> diffusion tensor imaging (DTI) and Clear Lipid-exchanged, Anatomically Rigid, Imaging/immunostaining compatible, Tissue hYdrogel (CLARITY) performed on intact mouse brains. DTI-derived measures of fractional anisotropy (FA), radial diffusivity (RD), and axial diffusivity (AD) were compared to antibody-based labeling of myelin basic protein (MBP), as measured by fluorescence microscopy. We used a customized CLARITY hydrogel solution to facilitate w ...[more]
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