Cytoarchitecture of Zika virus infection in human neuroblastoma and Aedes albopictus cell lines.
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ABSTRACT:
SUBMITTER: Offerdahl DK
PROVIDER: S-EPMC5201448 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Publications
Cytoarchitecture of Zika virus infection in human neuroblastoma and Aedes albopictus cell lines.
Offerdahl Danielle K DK Dorward David W DW Hansen Bryan T BT Bloom Marshall E ME
Virology 20161116
The Zika virus (ZIKV) pandemic is a global concern due to its role in the development of congenital anomalies of the central nervous system. This mosquito-borne flavivirus alternates between mammalian and mosquito hosts, but information about the biogenesis of ZIKV is limited. Using a human neuroblastoma cell line (SK-N-SH) and an Aedes albopictus mosquito cell line (C6/36), we characterized ZIKV infection by immunofluorescence, transmission electron microscopy (TEM), and electron tomography (ET ...[more]
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