Ontology highlight
ABSTRACT:
SUBMITTER: Enright HA
PROVIDER: S-EPMC5203773 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Enright Heather A HA Malfatti Michael A MA Zimmermann Maike M Ognibene Ted T Henderson Paul P Turteltaub Kenneth W KW
Chemical research in toxicology 20161011 12
Accelerator mass spectrometry (AMS) has been adopted as a powerful bioanalytical method for human studies in the areas of pharmacology and toxicology. The exquisite sensitivity (10<sup>-18</sup> mol) of AMS has facilitated studies of toxins and drugs at environmentally and physiologically relevant concentrations in humans. Such studies include risk assessment of environmental toxicants, drug candidate selection, absolute bioavailability determination, and more recently, assessment of drug-target ...[more]