Strong cis-acting expression quantitative trait loci for the genes encoding SNHG5 and PEX6.
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ABSTRACT:
SUBMITTER: Lee J
PROVIDER: S-EPMC5207599 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
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Strong cis-acting expression quantitative trait loci for the genes encoding SNHG5 and PEX6.
Lee Jihyeon J Ryu Jihye J Lee Chaeyoung C
Medicine 20161201 52
Expression of quantitative trait loci (eQTLs) for the genes located in human chromosome 6 were examined. Data on RNA expression in lymphoblastoid cells of 373 unrelated Europeans were used to identify eQTLs.Genome-wide analysis resulted in 24,447 nucleotide variants associated with gene expression (P < 2.16 × 10). We found 36variants with P < 10, which were all associated with expression levels of the genes encoding small nucleolar RNA host gene 5 (SNHG5) and peroxisomal biogenesis factor 6 (PEX ...[more]
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