Ontology highlight
ABSTRACT:
SUBMITTER: Beck EC
PROVIDER: S-EPMC5209355 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Beck Emily C EC Barragan Marilyn M Tadros Madeleine H MH Kiyotake Emi A EA Acosta Francisca M FM Kieweg Sarah L SL Detamore Michael S MS
Annals of biomedical engineering 20160107 6
Hydrogel precursors are liquid solutions that are prone to leaking from the defect site once implanted in vivo. Therefore, the objective of the current study was to create a hydrogel precursor that exhibited a yield stress. Additionally, devitalized cartilage extracellular matrix (DVC) was mixed with DVC that had been solubilized and methacrylated (MeSDVC) to create hydrogels that were chondroinductive. Precursors composed of 10% MeSDVC or 10% MeSDVC with 10% DVC were first evaluated rheological ...[more]