Identification of Potential Key lncRNAs and Genes Associated with Aging Based on Microarray Data of Adipocytes from Mice.
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ABSTRACT:
SUBMITTER: Yang Y
PROVIDER: S-EPMC5209599 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Identification of Potential Key lncRNAs and Genes Associated with Aging Based on Microarray Data of Adipocytes from Mice.
Yang Yi Y Teng Zongyan Z Meng Songyan S Yu Weigang W
BioMed research international 20161221
<i>Objective</i>. This study aimed to screen potential crucial lncRNAs and genes involved in aging. <i>Methods</i>. The data of 9 peripheral white adipocytes, respectively, taken from male C57BL/6J mice (6 months, 14 months, and 18 months of age) in GSE25905 were used in this study. Differentially time series expressed lncRNA genes (DE-lncRNAs) and mRNA genes (DEGs) were identified. After cluster analysis of lncRNAs expression pattern, target genes of DE-lncRNAs were predicted from the DEGs, and ...[more]
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