Ontology highlight
ABSTRACT:
SUBMITTER: Santin YG
PROVIDER: S-EPMC5210162 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Santin Yoann G YG Cascales Eric E
EMBO reports 20161205 1
The type VI secretion system (T6SS) is an anti-bacterial weapon comprising a contractile tail anchored to the cell envelope by a membrane complex. The TssJ, TssL, and TssM proteins assemble a 1.7-MDa channel complex that spans the cell envelope, including the peptidoglycan layer. The electron microscopy structure of the TssJLM complex revealed that it has a diameter of ~18 nm in the periplasm, which is larger than the size of peptidoglycan pores (~2 nm), hence questioning how the T6SS membrane c ...[more]