Dataset Information

InterPro in 2017-beyond protein family and domain annotations.

ABSTRACT: InterPro (http://www.ebi.ac.uk/interpro/) is a freely available database used to classify protein sequences into families and to predict the presence of important domains and sites. InterProScan is the underlying software that allows both protein and nucleic acid sequences to be searched against InterPro's predictive models, which are provided by its member databases. Here, we report recent developments with InterPro and its associated software, including the addition of two new databases (SFLD and CDD), and the functionality to include residue-level annotation and prediction of intrinsic disorder. These developments enrich the annotations provided by InterPro, increase the overall number of residues annotated and allow more specific functional inferences.

SUBMITTER: Finn RD

PROVIDER: S-EPMC5210578 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature

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Publications

InterPro in 2017-beyond protein family and domain annotations.

Finn Robert D RD Attwood Teresa K TK Babbitt Patricia C PC Bateman Alex A Bork Peer P Bridge Alan J AJ Chang Hsin-Yu HY Dosztányi Zsuzsanna Z El-Gebali Sara S Fraser Matthew M Gough Julian J Haft David D Holliday Gemma L GL Huang Hongzhan H Huang Xiaosong X Letunic Ivica I Lopez Rodrigo R Lu Shennan S Marchler-Bauer Aron A Mi Huaiyu H Mistry Jaina J Natale Darren A DA Necci Marco M Nuka Gift G Orengo Christine A CA Park Youngmi Y Pesseat Sebastien S Piovesan Damiano D Potter Simon C SC Rawlings Neil D ND Redaschi Nicole N Richardson Lorna L Rivoire Catherine C Sangrador-Vegas Amaia A Sigrist Christian C Sillitoe Ian I Smithers Ben B Squizzato Silvano S Sutton Granger G Thanki Narmada N Thomas Paul D PD Tosatto Silvio C E SC Wu Cathy H CH Xenarios Ioannis I Yeh Lai-Su LS Young Siew-Yit SY Mitchell Alex L AL

Nucleic acids research 20161129 D1

InterPro (http://www.ebi.ac.uk/interpro/) is a freely available database used to classify protein sequences into families and to predict the presence of important domains and sites. InterProScan is the underlying software that allows both protein and nucleic acid sequences to be searched against InterPro's predictive models, which are provided by its member databases. Here, we report recent developments with InterPro and its associated software, including the addition of two new databases (SFLD ...[more]

PMID: 27899635

Dataset Information

InterPro in 2017-beyond protein family and domain annotations.

Publications

InterPro in 2017-beyond protein family and domain annotations.

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