Ontology highlight
ABSTRACT:
SUBMITTER: Cai D
PROVIDER: S-EPMC521148 | biostudies-literature | 2004 Sep
REPOSITORIES: biostudies-literature
Cai David D Tao Louis L McLaughlin David W DW
Proceedings of the National Academy of Sciences of the United States of America 20040920 39
To address computational "scale-up" issues in modeling large regions of the cortex, many coarse-graining procedures have been invoked to obtain effective descriptions of neuronal network dynamics. However, because of local averaging in space and time, these methods do not contain detailed spike information and, thus, cannot be used to investigate, e.g., cortical mechanisms that are encoded through detailed spike-timing statistics. To retain high-order statistical information of spikes, we develo ...[more]