Ontology highlight
ABSTRACT:
SUBMITTER: Kong N
PROVIDER: S-EPMC5214687 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Scientific reports 20170105
Mammalian spermatozoa undergo selective movement along the isthmus of the oviduct to the ampulla during ovulation, which is a prerequisite for fertilization. The factor(s) that involves in selective spermatozoa movement is still unknown. In this study, we found that the oviductal epithelium in mouse ampulla expressed high levels of natriuretic peptide type C (NPPC) in the presence of ovulated oocyte-cumulus complexes (OCCs). Spermatozoa expressed NPPC receptor natriuretic peptide receptor 2 (NPR ...[more]