Can individualized sunitinib dose and schedule changes optimize outcomes for kidney cancer patients?
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ABSTRACT:
SUBMITTER: Bjarnason GA
PROVIDER: S-EPMC5215304 | biostudies-literature | 2016 Nov-Dec
REPOSITORIES: biostudies-literature
Publications
Can individualized sunitinib dose and schedule changes optimize outcomes for kidney cancer patients?
Canadian Urological Association journal = Journal de l'Association des urologues du Canada 20161101 11-12Suppl7
The recommended starting dose and schedule for sunitinib is 50 mg daily for 28 days, followed by a 14-day break with significant dose reductions to 37.5 mg (75% of starting dose), and then 25 mg (50% of starting dose) on the same schedule (four/two schedule). There are several reasons why these dose and scheduling recommendations may not be optimal for most patients, as outlined below. ...[more]
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